(Reference: 臺北榮民總醫院 血液成分使用準則)

急性出血且失血量大於全身血量之 25 %以上 pRBC : FFP : plt pheresis = 8 : 8 : 1 (也等於 1:1:1 plt concentrate)

(Reference: 臨床經驗)

• breast master 老師: 習慣是 10u pRBC : 10u FFP : 1u Platelet Pheresis

(Reference: Miller’s, 9th ed. Ch.49)

Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) study, Holcomb

• severe trauma and major bleeding
• early administration of plasma, platelets, and red blood cells in a 1:1:1 ratio versus a 1:1:2 ratio did not result in significant differences in mortality at 24 hours or at 30 days.
• ⇒ pRBC : FFP : Plt = 2:1:1 or 1:1:1 沒差 (這裡的 platelet 我讀起來應該是指 platelet concentrate)

[這段 Miller 有一段滿重要的觀念]

These aggressive uses of FFP, platelets, and other blood products have only been shown to be beneficial in response to coagulopathies from massive blood transfusions. Aggressive plasma administration to other transfused patients was associated with an increased rate of serious complications, including acute respiratory distress syndrome (ARDS) and organ dysfunction.

⇒ 不然多輸這些除了 RBC 之外的血品 ⇒ 增加其他 complication

!所以 ⇒ 注意 coagulopathy